Metered-Dose Inhaler Spacer

Increasing numbers of children and seniors require inhalation therapy for asthma, and other pulmonary diseases. Metered Dose Inhalers (MDIs) dispense aerosolized drugs that are inhaled by patients. An inhaler spacer reduces aerosol droplet size by evaporation for deep lung penetration. This also reduces the number of larger droplets that deposit in the upper airways, get swallowed, and contribute to side effects.

Advantages of the CFDRC Spacer:

Compared to available MDI inhaler spacers, the CFDRC spacer provides:

  • Less Drug Loss on Spacer Walls,
  • More Drug Deep into Lungs
  • Easier Inhalation

The conical shape of the CFDRC spacer is combined with air slits to generate an air cushion that keeps drug aerosols off of the spacer walls. Mixing outside air with the dispensed spray inside the spacer slows the flow of drug, allowing more time for evaporation and reducing the size of droplets. Introducing outside air also makes inhalation easier for breathing impaired patients by reducing resistance.

In addition to its drug delivery advantages, the conical shape of the CFDRC spacer can also be made collapsible for convenient storage.

A unique one-way valve, modeled after the tricuspid valve in the heart, opens more easily than other valves during inhalation and closes completely during exhalation. This helps breathing impaired patients to get more dispensed drug deep into the lungs and to hold the drug there longer before exhaling.

Computer simulations and prototype testing indicate that the CFDRC inhaler spacer delivers up to 15% more drug with up to 30% higher efficiency than the market leader. Details of test results are available to parties interested in licensing the Inhaler Spacer.