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Biomedical and Life Sciences

Respiratory Drug Delivery

CFDRC is the leading provider of total engineering solutions for respiratory device design and analysis. CFDRC has developed the simulation technologies to model complex non-linear interactions of physical phenomena including fluid flow, heat transfer, mass transfer, aerosol spray transport that need to be well understood in the effort to design and build better pulmonary delivery systems.

Simulation of Aerosol Transport in Inhaler Devices
More than half of the dispensed drug is lost by deposition within an inhaler. CFDRC engineers routinely analyze and optimize drug delivery (minimize deposition) of inhalers and accessories.

Metered-Dose Inhaler
Dry Powder Inhaler

Simulation of Aerosol Transport in Human Airways
A further significant fraction (30-50%) of a drug is lost by deposition in the back of the throat. CFD-ACE+ is used to analyze the throat deposition patterns for specific inhaler designs.

In-vitro Characterization of Inhaler Devices
Fully complementing the simulations, the CFDRC Biofluids lab is well-equipped to perform experiments characterizing medical sprays and delivered dosage.

 
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